Programme
18 October, Tuesday, Day 1
| 10:30 - 15:00 |
Session 1 Chair: Uschi Symmons |
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| 10:30 - 11:30 | Esther Schnapp: Publishing policies and Initiatives at EMBO press | |
| 11:30 - 12:30 | Helena Jambor: How not to lie with (biomedical) charts | |
| 12:30 – 13:00 | Break | |
| 13:00 – 15:00 | Being a data detective: Helena Jambor: Take a sad plot and make it better - Better figures in the biological sciences |
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| 12:00 – 15:30 | Registration | |
| 15:15 – 15:30 | Conference Opening | |
| 15:30 – 18:15 | Session 2 Epigenetics and development Chair: Petra Hajkova |
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| 15:30 – 16:00 | Deborah Bourc’his: Epigenetic determinants of germline specification and protection | |
| 16:00 – 16:15 | Emmanuel Cazottes: Rapid evolution of non-coding regulators of X-inactivation across primates | |
| 16:15 – 16:30 | Ariella Weinberg-Shukron: Balanced gene dosage control rather than parental origin underpins genomic imprinting | |
| 16:30 – 17:00 | Coffee break | |
| 17:00 – 17:30 | Juanma Vaquerizas: Gene regulation in human spermatogenesis | |
| 17:30 – 17:45 | Tomasz Jurkowski: Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function | |
| 17:45 – 18:15 | Jop Kind: The chromatin landscape during early embryo development at single-cell resolution |
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| 18:30 – 19:30 | Session 3 Keynote Lecture Chair: Petra Hajkova |
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| 18:30 – 19:30 | Marisa Bartolomei: Epigenetic regulation of imprinted gene clusters | |
| 20:00 – | Welcome dinner ELTE Lágymányosi Campus, Globe Hall |
19 October, Wednesday, Day 2
| 08:30 – 09:30 | Breakfast with the invited speakers (in speakers’ hotel, maximum 3 students / speaker, registration for the programme is needed in advance) |
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| 09:00 – 10:00 | Registration | |
| 10:00 – 11:00 | Session 4 Epigenetics and transcription Chair: Tibor Pankotai |
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| 10:00 – 10:30 | László Tora: Two related coactivator complexes, SAGA and ATAC, control embryonic stem cell self-renewal through two different acetyltransferase-independent mechanisms | |
| 10:30 – 10:45 | Gábor Pápai: SAGA saga or, how TBP is deposited on DNA | |
| 10:45 – 11:00 | Nabieh Ayoub: Transcriptional regulation at DNA double-strand break sites: A spotlight on Lysine Crotonylation | |
| 11:00 - 11:30 | Coffee Break | |
| 11:30 – 12:00 | Yitzhak Reizel: FoxA pioneer factors and TET proteins establish a stable epigenetic signature in hepatocytes | |
| 12:00 – 12:15 | Jannat Ijaz: Epigenetic and transcriptomic alterations caused by shattered chromosomes | |
| 12:15 – 12:30 | Yoav Voichek: Controlling transcription from within transcribed regions in plants | |
| 12:30 – 13:00 | Dirk Schübeler: Beyond motif: guiding sites of transcription factor binding by DNA modifications | |
| 13:00 - 14:30 | Lunch break | |
| 14:30 - 17:00 | Poster session I. |
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| 16:30 - 17:00 | Coffee break | |
| 17:00 - 19:30 | Session 5 Epigenetics and differentiation Chair: Tamás Arányi |
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| 17:00 – 17:30 | Marc Bühler: Genetic alterations precede epigenetic gene silencing | |
| 17:30 – 17:45 | Melinda Bence: Drosophila piwi protein utilizes molecular mimicry of Sumo to recruit SU(VAR)2-10 to the site of transposon repression | |
| 17:45 – 18:00 | Suzan Stelloo: Deciphering lineage specification during early embryogenesis using multi-layered proteomics | |
| 18:00 – 18:30 | Wolf Reik: Single cell multi-omics landscape of development and ageing | |
| 18:30 – 18:45 | Raffaele Teperino: Parental genetics and epigenetic programming of offspring phenotypes | |
| 18:45 – 19:00 | Christopher Douse: Layered epigenetic control of transcribed repetitive elements in human brain development | |
| 19:00 – 19:30 | Sara Annika Wickström: Regulation of stem cell fate by nuclear mechanotransduction | |
| 20:00 - | Beer session / Meet the lecturers Cactus Juice Gastro Pub, 1061 Budapest, Jókai tér 5. |
20 October, Thursday, Day 3
| 08:30 – 09:30 | Breakfast with the invited speakers (in speakers’ hotel, maximum 3 students / speaker, registration for the programme is needed in advance) | |
| 10:00 – 13:00 | Session 6 Epigenetics and physiology Chair: Lóránt Székvölgyi |
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| 10:00 – 10:30 | J. Andrew Pospisilik: Epigenetic underpinnings of metabolic disease heterogeneity | |
| 10:30 – 10:45 | Ilaria Panzeri: Developmental Plasticity as a Predisposing Factor for Tumorigenesis | |
| 10:45 – 11:00 | Iván P. Uray: Winner of HBS Epigenetics Section Award Pharmacologic targeting of ARID1A for the non-estrogenic modulation of IGF-1 signaling |
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| 11:00 – 11:30 | Coffee Break | |
| 11:30 – 12:00 | Richárd Bártfai: Epigenetically-regulation of RNA-binding proteins underlies dormancy of relapsing malaria parasites | |
| 12:00 - 12:15 | Javier Redondo-Muñoz: Functional and mechanical response of epigenetic changes in leukemia cells | |
| 12:15 – 12:45 | Amos Tanay: Competition and compensation in the epigenetic dynamics of embryonic multifurcation | |
| 12:45 - 14:30 | Lunch break | |
| 14:30 - 17:00 | Poster session II. |
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| 16:30 - 17:00 | Coffee break | |
| 17:00 - 19:00 | Session 7 Genome architecture Chair: J. Andrew Pospisilik |
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| 17:00 - 17:15 | Mutay Aslan: Introducing FEBS activities and programmes | |
| 17:15 – 17:45 | Lóránt Székvölgyi: Unravelling the genetic architecture of R-loops and chromatin loops | |
| 17:45 – 18:15 | Giacomo Cavalli: Epigenetic regulation of 3D genome architecture in cell differentiation and development | |
| 18:15 – 18:30 | László Imre: Epigenetic modulation based on the fundamental role of the C-terminal tail of H2A.Z in determining nucleosome stability, accessibility of DNA in chromatin and nuclear architecture | |
| 18:30 – 19:00 | Bas van Steensel: Using random scrambling to decode sequence determinants of nuclear organisation | |
| 19:30 - | Gala dinner |
21 October, Friday, Day 4
| 09:30 – 13:00 | Session 8 Epigenetics and inheritance Chair: László Tora |
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| 09:30 – 10:00 | Celia P. Martinez-Jimenez: Effect of ageing on cellular variability and transcriptional dynamics | |
| 10:00 – 10:15 | Dick Zijlmans: Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction | |
| 10:15 – 10:30 | Ioannis Kafetzopoulos: Reiterative de novo methylation maintains methylation levels in somatic cells | |
| 10:30 – 11:00 | Coffee Break | |
| 11:00 – 11:30 | Ferenc Mueller: Epigenomic organisation and mammalian conservation of cis-regulatory landscape during zebrafish development | |
| 11:30 - 11:45 | Jose Perez-Mojica: Continuous transcriptome analysis of single embryos reveals novel early transcriptional programs in Drosophila melanogaster | |
| 11:45 – 12:00 | Kristeli Eleftheriou: Dynamic changes in chromatin configurations in late oogenesis impact the epigenome of the early embryo | |
| 12:00 – 12:30 | Petra Hajkova: Stability, turnover and erasure of epigenetic information in vivo | |
| 12:30 - 13:00 | Prizes and concluding remarks | |
| 13:00 - 14:30 | Farewell snacks |
Posters list
Each poster might be mounted during the whole Conference. The recommended poster size is a standing A/0 (84 cm x 119 cm) as the size of the poster board is 90 cm at width and 120 cm at height. Posters left on the boards after the removal deadline will be removed by the organisers.
Mounting: October 18, from 12:00
Removal: October 21, till 13:00
Technical instructions:
Posters should be prepared for standard STANDING (PORTRAIT) A/0 size (84 x 119 cm – 1 sqm). PLEASE DO NOT PRINT A LANDSCAPE POSTER!
The organisers provide pins to mount your poster to the board at the conference venue and they will be at your disposal if you need help.
| P-01 | Fatima Al-Ali Investigating functional consequences of Mcts2 during Embryonic Development |
| P-02 | Tamás Arányi IMPROVE-RRBS tool Ignores MsPI site and sequencing Read 3’ end OVErlap in RRBS methylation calling |
| P-03 | Marie-Thérèse Bammert Fueling aberrant cell populations – Metabolic dysregulation drives the progression of pulmonary fibrosis |
| P-04 | Damir Baranasic Dynamics and locus organisation of enhancers regulating key factors in early zebrafish development |
| P-05 | Ivona Beceheli The association between cord blood DNA methylation of serotonin-regulating genes and body fat-related characteristics in newborns |
| P-06 | Angéla Békési Conditions of drug induced enzymatic DNA cytosine deamination and genomic uracil profiles. |
| P-07 | Krisztián Bene The roles of the transcriptional repressor BACH1 in regulating the differentiation of macrophages |
| P-08 | Jahnavi Bhaskaran Characterisation of molecular mechanisms of healthy spermatogenesis in humans |
| P-09 | Dóra Bojcsuk Locus-specific genomic rearrangement of the transcriptional repressor BACH1 upon heme treatment supports transcription |
| P-10 | Thomas Boutet Unravelling the „inflammatory-chromatin“ epigenetic code using Drosophila genetics |
| P-11 | Aimée Rodica Chis TIME DEPENDENT EXPRESSION OF MMU-MIR-195 IN MOUSE HEART |
| P-12 | Zeina Esmandar Epigenomic changes upon expression of the transposase-derived SETMAR histone methylase in the human genome |
| P-13 | Norbert Gődér Examination of 3D genome conformation related to R-loops |
| P-14 | Karolina Gronkowska Paclitaxel treatment induces BRG1-dependent chromatin remodelling at the promoters of lysosome-localized ABC transporters and confers multidrug resistance |
| P-15 | Eliza Guti Metformin-induced changes in transcriptomic profile of MCF-7 hormone receptor positive breast carcinoma cell line |
| P-16 | Renáta Hamar Uncovering the complexity of zebrafish (Danio rerio) snoRNAome |
| P-17 | Emma Hands The Role of Methylation in the Formation of Pathological R-loops |
| P-18 | Eszter Holub Altered cell responses induced by two thymidylate synthase inhibitory drugs |
| P-19 | Elizabeth Ing-Simmons Single-nucleus multiomic analysis of gene regulation in human spermatogenesis |
| P-20 | Sham Jdeed ARID1A mediates the anti-proliferative effects of bexarotene and carvedilol in normal and transformed breast cells |
| P-21 | Alexandra Kalmár Genome-wide expression profiling in colorectal cancer focusing on lncRNAs in the adenoma-carcinoma transition |
| P-22 | Kyu-Tae Kim Exploring the impact of clonal mosaicism in the blood system on cardiac inflammation |
| P-23 | Lilla Kókity ROLE OF EPIGENETIC REGULATOR RYBP IN CARDIAC LINEAGE COMMITMENT |
| P-24 | YuHao Liu Deciphering The Functions of The Lateral Modifications during Early Developmental Process |
| P-26 | Barbara Kinga Molnár Analyzing the methylation pattern of cell-free DNA for monitoring the chemotherapy response of colorectal cancer patients |
| P-27 | Iraia Muñoa Hoyos Chronic morphine treatment prevents the X-chromosome inactivation (XCI) |
| P-28 | Dalma Müller Integrated dataset of methylome data of colorectal normal, adenoma and adenocarcinoma tissues enables ranking of methylation changes in distinct gene-associated regions |
| P-29 | Gergely Nagy Dissecting the cistromes determining bone marrow-derived macrophages |
| P-30 | Zsófia Brigitta Nagy Folic acid combined chemotherapy has an immediate effect on c1-methionin cycle and consequential dna methylation in liquid biopsy samples of colorectal cancer patients |
| P-31 | Subirán Nerea SMCHD1 is a key regulator of epigenetic cellular memory induced by morphine |
| P-32 | Henri Niskanen Hijacking of transcriptional condensates by endogenous retroviruses |
| P-33 | Ainize Odriozola Morphine leads to a global hipometylation via active and pasive demetilation mechanisms in mESCs |
| P-34 | Gabrielle Oxley Exploring the effects of drug exposure on the developing epigenome using in vitro models |
| P-35 | Gábor Papp Correlation between uracilation and transcriptional activities in drug treated colon cancer cells |
| P-36 | Máté Posta Whole genome transcriptomic changes in the placenta suggests epigenetic origins of recurrent pregnancy loss |
| P-37 | Aurél Prósz Biologically informed deep learning for explainable epigenetic clocks |
| P-38 | Mirabela Romanescu Therapy induced microRNA modifications in Parkinson’s disease |
| P-40 | Hussein Sabit Paclitaxel-loaded casein nanoparticles induces apoptosis in breast cancer cells via MAPK pathway |
| P-41 | Hussein Sabit CRISPR/Cas9-mediated activation of CDH1 suppresses metastasis of breast cancer in rats |
| P-42 | Iris Šalamon Arčan H3K14ac is decreased through genome in Slovenian male suicide completers |
| P-43 | Kristine Salmina Amoeboid transition in polyploid breast cancer cells induced after genotoxic treatment is essential for clonogenic resistance |
| P-44 | Federica Sarno Integrated biological and chemical epigenetic-targeting platform to improve cancer therapy |
| P-45 | Aimee Chis, (Ovidiu Sirbu) Altered circulating hsa-miR-195-5p level predicts Covid-19 severity in hospitalized patients |
| P-46 | Vaidotas Stankevicius DNMT1 specific covalent tracing of DNA methylation in mouse embryonic cells |
| P-47 | Krisztina Szigeti Global DNA hypomethylation could be linked to decreased methyl-donor content in colorectal cancer progression |
| P-48 | Pia Todtenhaupt Mesenchymal stromal cells as a tool to unravel the epigenetic mechanism underlying the developmental origins of disease |
| P-49 | Dániel Tóth Generation and characterization of hepatocyte-specific DNA methyltransferase (Dnmt) 3a and Dnmt3b double knockout mice. |
| P-50 | Kayla Townsley Convergent impact of schizophrenia risk genes |
| P-51 | Sára Zsigrai Epigenetic reprogramming of colorectal cancer cell lines by S-adenosylmethionine treatment |
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