Scientific program

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Wednesday, October 5
Venue: Hungarian Academy of Sciences

14:00-Registration
16:00-16:30Introduction
16:30-17:30Keynote Lecture
  • Eileen Furlong
    Functional insights into chromatin topology and gene expression during embryonic development
    Sponsored by:
    embo
17:30-19:00
Single-cell epigenetics
17:30-18:00Alexander van Oudenaarden
Revealing novel cell types, cell-cell interactions, and cell lineages by single-cell sequencing
18:00-18:15Juliette Dabin
Contribution of parental histone dynamics to epigenome stability after DNA damage
18:15-18:30 Zichuan Liu
Daxx and PRC1 control integrity and segregation of paternal chromosomes in mouse early embryos
18:30-19:00Mario Nicodemi
Hierarchical folding of chromosomes in neuronal differentiation and its link to epigenetics
19:00-19:15Coffee break
19:15-20:00
Single-cell epigenetics
19:15-19:30Guillaume Filion
HIV and human chromatin
19:30-20:00Christoph Bock
Epigenetic biomarkers: Ready for clinical diagnostics
Sponsored by:
logo diagenode


20:00-Welcome dinner

Thursday, October 6
Venue: RCNS

 

8:00-Registration
9:00-10:30
Metabolism and epigenetics

9:00-9:30

Iannis Talianidis
H4K20 monomethylation regulates RNA Pol-II elongation and plays an important role in the transcriptional control of hepatic metabolic pathways
9:30-9:45Florence Cammas
Functions of the HP1 network in liver homeostasis
9:45-10:00Tamas Arányi
Dynamic DNA methylation changes due to acute metabolic stress in mice
10:00-10:30Ueli Schibler
Posttranscriptionally controlled ribosome assembly rhythms drive diurnal cycles in global liver mass and macromolecular content
10:30-11:00Coffee break & Group photo
11:00-12:00
Metabolism and epigenetics
11:00-11:15Sabine Fraschka
Deciphering the transcriptional regulatory network of the human malaria parasite Plasmodium falciparum
11:15-11:30Tibor Pankotai
Transcriptional outcomes in response to DNA damage
11:30-12:00Andrew Pospisilik
β-cell PRC2 focuses transcription of select lineage genes and thus prevents de-differentiation and Diabetes in mouse and Man
12:00-13:00Lunch break
13:00-14:30
Developmental epigenetics
13:00-13:30Petra Hajkova
Epigenetic reprogramming in vivo: How and why?
13:30-13:45Pierre-Antoine Defossez
A histone mimic within DNA Ligase 1 recruits UHRF1 to sites of DNA replication: implications for DNA remethylation
13:45-14:00Ivett Baksa
Small RNA-based regulation during temperature adaptation in Arabidopsis
14:00-14:30Amos Tanay
Single cell approaches to cellular memory
14:30-15:00Coffee break
Live DEMO Show on the exhibition booth of  biomarker  qlogo_50mm
  • Single cell analysis with QIAGEN: sample prep, amplification, NGS library prep and targeted panels
  • Fast and cost-effective methylation studies with a fully automated QIAGEN workflow (QIAcube, Rotor-Gene Q, Pyromark Q48 Advanced)
15:00-15:45
Developmental epigenetics
15:00-15:15Alessio Zippo
MYC favors the onset of tumorigenesis by inducing epigenetic reprogramming of mammary epithelial cells towards a stem cell-like state
15:15-15:45Ferenc Mueller
Developmental dynamics of epigenomic features of cis-regulatory elements in early embryo development
15:45-16:15Coffee break
16:15-18:00Poster viewing
19:30-Social program (Beer session)
Optional program, costs not covered by the registration fee

Friday, October 7
Venue: RCNS

8:00-Registration
9:00-10:30
Chromatin architecture
9:00-9:30Ana Pombo
Genome Architecture Mapping: A spatial approach to map chromatin contacts
9:30-9:45Judit Balog
Heterozygous mutations in DNMT3B cause derepression of the subtelomeric D4Z4 macrosatellite array and contribute to the development of muscle disease
9:45-10:00Lóránt Székvölgyi
A Set1C-entric view of meiotic recombination initiation
10:00-10:30Leonie Ringrose
Beyond memory: The secret life of Polycomb Response Elements
10:30-11:00Coffee break
11:00-11:45
Chromatin architecture
11:00-11:15Irene Cantone
Cell fusion-mediated reprogramming reveals a link between variability of human X chromosome inactivation in somatic cells and pluripotency-induced gene reactivation
11:15-11:45Wouter de Laat
Multi-contact 4C reveals multi-way three-dimensional chromatin conformation
11:45-13:45Poster session
13:45-20:00Sandwiches
Free afternoon
20:00-Gala Dinner – Danube cruise

Saturday, October 8
Venue: RCNS

8:00-Registration
9:00-10:30
Transcriptional regulation and epigenetics
9:00-9:30Laszlo Tora
The ATAC and SAGA coactivator complexes are highly dynamic in the nuclear environment with fast and slow chromatin interacting populations
9:30-9:45Salvatore Spicuglia
Epromoters define a new class of regulatory elements with dual promoter and enhancer functions in mammals
9:45-10:00Chantal Vaury
Silencing of transposable elements by PIWI-interacting RNAs
10:00-10:30Tamas Fischer
Epigenetic control of pervasive transcription and genomic stability
10:30-10:50Coffee break
10:50-11:35
Transcriptional regulation and epigenetics
10:50-11:05Bálint L. Bálint
Super-enhancers and person-to-person genetic variability in the context of the 1000 Genomes Project
11:05-11:35Michaela Frye
RNA methylation in stem cells and cancer
11:35-13:00Lunch break and poster viewing
13:00-14:30
Transgenerational inheritance
13:00-13:30Vincent Colot
Transgenerational Epigenetics: Lessons from Arabidopsis
Sponsored by:
IF_Logo Budapest-Quadri_2011
13:30-13:45Aman Zare
Drosophila gut microbiome is involved in transgenerational inheritance of acquired traits
13:45-14:00Kallayanee Chawengsaksophak
The epigenetic modifier Fam208a is essential for mouse gastrulation
14:00-14:30Erica Watson
How abnormal folate metabolism haunts our descendants
14:30-Poster prizes and concluding remarks

Posters

P-01

Hakan Akca
miR-548as could be a novel suppressor of TGFβR1 to inhibit epithelial-to-mesenchymal transition in NSCLC

P-02

Caroline Bacquet
Applying environmental epigenomics to assess adaptation to global change in Heliconius melpomene butterfly populations

P-03

Marine Baptissart
Developmental programming in response to maternal overnutrition

P-04

Raymond Blind
Readers, writers and erasers of nuclear PIP3

P-05

Laszlo Bodai
Exploring the role of histone modifications in Huntington’s disease

P-06

Dóra Bojcsuk
Canonical elements drive super-enhancer formation

P-07

Pedro Castelo-Branco
Hypermethylation of the TERT promoter predicts biochemical relapse
in prostate cancer

P-08

Vin Yee Chung
The interplay between transcription factor GRHL2 and epigenetics in the regulation of EMT in ovarian cancer

P-09

Sébastien Coassolo
Role of the chromatin-remodelling complex NURF and NuRD in epigenetic regulation of melanoma gene expression

P-10

Ixchelt Cuaranta Monroy
Genome-wide studies during adipocyte differentiation from mouse pluripotent stem cells

P-11

Luiza Diniz Ferreira Borges
Epigenetic in the development: Detection of histones deacetylases in melipona scutellaris (apidae, meliponini)

P-12

Edina Erdős
Genome-wide mapping of COUP-TFII and ERa co-occupancy in breast cancer cells

P-13

Sercan Ergun
In silico analysis of potential cernas in renal cell carcinoma

P-14

Sercan Ergun
Analysis of 3’UTR shortening of ABCB1 gene in Imatinib-resistant CML cells in terms of potential ceRNAs by a computational study

P-15

Dominique Fauvin
Next generation epigenetics – Innovative research tools for the accurate analysis of DNA modifications

P-16

Erfaneh FirouziNiaki
Histone type, modification and cell cycle phasespecific characterization of nucleosome stability in situ

P-17

Erfaneh FirouziNiaki
Measurement of interstrand DNA crosslinks generated by anticancer agents through a modified alkaline comet assay

P-18

Anna Fortuny Gonzalez
Histone dynamics in response to DNA damage in heterochromatin domains

P-19

Marybeth Francis
Inflammation differentially affects histone methylation state of promoters of inflammatory genes and structure proteins

P-20

Zsuzsanna Gaál
Expression levels of Warburg-effect related microRNAs in hematological malignancies of the adults

P-21

Kay Gully
Molecular mechanisms of elicitor-induced epigenetic changes in Apple and Arabidopsis thaliana

P-22

Anca-Sarmiza Gültekin-Tigan
The cyclin-dependent kinase CDK6 as key regulator of the cancer epigenome

P-23

Attila Horváth
Characterization and modeling of lineage-specific enhancer states and transitions in macrophages

P-24

Mette Jacobsen
Adipocyte gene expression and DNA methylation patterns differ significantly between lean and obese pigs.

P-25

Aeri Kim
Erythroid activator NF-E2, TAL1 and KLF1 play roles in forming the LCR HSs in the human adult β-globin locus

P-26

Gergő Kovács
Rybp plays essential role in neural differentiation of mouse embryonic stem cells

P-27

Janina Ličytė
Direct decarboxylation of 5‑carboxylcytosine by DNA C5- methyltransferases

P-28

Cha Min Ho
Free hemoglobin change gene expression involving in cell-cell signaling through different DNA methylation in THP-1-derived macrophages

P-29

Celine Morey
The non-coding gene Ftx promotes Xist upregulation at the onset of
X-chromosome inactivation

P-30

Iraia Muñoa Hoyos
The epigenetic regulator complex Polycomb/H3K27me3 plays a role in the epigenetic memory induced by morphine upon EpiLC differentiation

P-31

Gergely Nagy
IL-4 reshapes the RXR cistrome in mouse bone marrow-derived macrophages

P-32

Péter Nánási
The effect of histone modifications and DNA superhelicity on nucleosome stability

P-33

Péter Nánási
Nucleosome stability through the spectacles of quantitative imaging

P-34

Csilla Emese Németh
Epigenetic role of Vitamin C in the pathomechanism of Arterial Tortuosity Syndrome

P-35

Zsofia Nemoda
Controlling for cell composition of peripheral biological samples in candidate gene DNA methylation analyses

P-36

Dragos Nica
Association of global DNA hydroxymethylation with cadmium in gastropod hepatopancreas

P-37

Tünde Nyiko
Functional and molecular characterization of an epigenetically controlled PUMILIO-regulatory protein in Arabidopsis.

P-38

Colleen O’Ryan
Differential DNA methylation associated with Autism Spectrum Disorder in a South African cohort

P-39

Colleen O’Ryan
The serotonin transporter gene (SLC6A4) shows differential regulation between children with ASD and typically developing children in a South African population

P-40

Lilla Ozgyin
Genomic determinants of molecular phenotype differences between
B-lymphobastoid cells of a CEU trio

P-41

Luca Pagliaroli
MicroRNA regulation in Tourette Syndrome candidate genes

P-42

Luca Pagliaroli
Changes in DNA methylation profiles followed by sub-chronic treatment with psychiatric drugs aripripazole and riluzole in the rat striatum and prefrontal cortex

P-43

Cristina Popescu
Dynamic changes of epigenetic biomarkers (5mC and 5hmC) in biofluids of prostate cancer patients undergoing hormonal treatment

P-44

Petra Priščáková
Plasma DNA methylation profiles of genes associated with metastasis in breast cancer patients

P-45

Vanda Repiská
Methylation of genes associated with invasiveness of breast cancer

P-46

Helene Royo
The histone H3 lysine 36 demethylase KDM2A/FBXL11 is essential for Polycomb-mediated gene repression during germ cell development

P-47

Hussein Sabit
Epigenetic regulation of P21, RASSF1, PTEN, and P53 in human breast cancer cells using different chemotherapeutic drugs

P-48

Osama Said       
Procaine induces epigenetic changes in HCT 116 colon cancer cells

P-49

Kristine Salmina
Retrotransposition caused and autophagy-aided heterochromatin release in etoposide treated senescent teratocarcinoma PA1 cells

P-50

Rita Seeböck
What happens to the Epigenome in 2D/3D cell culture?

P-51

Ioan-Ovidiu Sirbu
qRT-PCR evaluation of selected microRNAs’ expression in amniotic fluid and chorionic villus samples from Down syndrome pregnancies

P-52

Ioan-Ovidiu Sirbu
Plasma microRNA expression profiles in Parkinson’s disease

P-53

Gordana Supic
miR-183 and miR-21 Expression as Biomarkers of Progression and Survival in Tongue Carcinoma Patients

P-54

Gábor Szabó
The effect of histone modifications and DNA superhelicity on nucleosome stability

P-55

Agnes Tantos
Intrinsic protein disorder in histone lysine methylation

P-56

Violeta Trusca
Apolipoprotein E upregulation by dexamethasone in macrophages

P-57

Borbála Vető
Inhibition of DNA methyltransferase leads to increased genomic
5-hydroxymethylcytosine levels in lymphoid cells

 

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